| 肾癌术后应用α-干扰素的疗效观察 |
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| 引用本文： | 贺会兴,于满,王云鹏,何宝玉,彭永光,刘德风,邱敏. 肾癌术后应用α-干扰素的疗效观察[J]. 临床合理用药杂志, 2012, 0(31): 40-41 |
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| 作者姓名： | 贺会兴 于满 王云鹏 何宝玉 彭永光 刘德风 邱敏 |
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| 作者单位： | [1]承德医学院附属医院泌尿科,河北省承德市067000 [2]武警河北总队医院泌尿科,石家庄市050086 [3]北京普仁医院外科,北京市100062 [4]河北省迁西县人民医院外科,064300 [5]北京大学首钢医院吴阶平泌尿外科医学中心,北京市100144 [6]北京大学第三医院泌尿外科,北京市100083 |
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| 摘 要： | 目的观察肾癌术后应用α-干扰素(α-IFN)的治疗效果。方法肾癌患者102例随机分为治疗组52例和对照组50例。治疗组肾癌切除术后应用α-IFN治疗,对照组单纯行肾癌切除术治疗。比较2组治疗效果。结果 2组早期(Robson分期Ⅰ～Ⅱ期)肾癌患者5年生存率差异无统计学意义(P>0.05);治疗组晚期(Ⅲ期)肾癌患者5年生存率明显高于对照组,差异有统计学意义(P<0.05)。结论晚期(Ⅲ期)肾癌切除术后应用α-IFN治疗能延长患者生存期,提高长期生存率,值得临床推广应用。
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| 关 键 词： | 干扰素 肾肿瘤 生物治疗 |
Efficacy analysis of a-interferon in the treatment of renal cell carcinoma after nephrectomy |
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| Affiliation: | HE Hui-xing , YU Man, WANG Yun-peng, et al. Department of Urology, Chengde Medical College, Chengde, Hebei 067000, China |
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| Abstract: | Objective To observe the effect of or-interferon（a-IFN） in the treatment of renal cell carcinoma after nephrectomy. Methods 102 cases patients with renal cell carcinoma were randomly divided into therapeutic group （52 cases ） and control group（50 cases）. Terapeutic group treated by ct-IFN after nephrectomy ,control group treated with nephrectomy alone. Compared the effect of two groups. Results The difference of the 5-year survival of（ Robson stage I - II ） between two group was no statistical significance（ P 〉 0.05 ） ;The 5-year survival rates in treatment group（ stage III ） was significantly higher than that in control group, the difference was statistically significant （ P 〈 0.05 ）. Conclusion The application of a-IFN in III period renal cell carcinoma after nephreetomy can prolong survival and improve long-term survival, worthy of clinical application. |
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| Keywords: | a-interferon Renal cell carcinoma Biological treatment |
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