应用彩色多普勒超声对胎儿畸形诊断的研究

目的研究规范化的产前彩色多普勒超声检查对胎儿畸形的诊断价值、诊断时机,分析各类畸形的分布及发生情况,了解产前超声检查易漏诊的疾病并分析漏诊原因。方法对8665例胎儿应用规范化标准切面进行超声筛查,并跟踪随访产后及引产后结果。结果共检出畸形胎儿213例,以神经系统、泌尿系统、唇腭裂、先天性心脏畸形、消化系统畸形发病率较高,排序前5位。漏诊畸形18例,漏诊的主要疾病为多指（趾）,肛门闭锁及耳异常。胎儿畸形最佳筛查时间为孕20-24周,但孕32-36周的超声检查必不可少,可明显增加消化系统畸形、胎儿肿瘤、胎儿膈疝、唇腭裂的检出率。结论超声检查可实时观察胎儿各部位、各器官的情况,可重复性强,规范化的产前超声检查可增加胎儿畸形的检出情况。

Study on the diagnosis of fetal malformations applying color Doppler ultrasound

Objective To study the diagnostic value and diagnosis timing of standardized prenatal color Doppler ultrasound to the diagnosis of fetal malformations,to analyze the distribution and the occurrence of various kinds of malformations,and to identify the diseases that can be easier misdiagnosed by prenatal color Doppler ultrasound and examine the root cause.Methods A screening on 8665 fetuses applying standardized criteria for section was done,and followed-up on the result after births or artificial abortion operations were made.Results A total of 213 cases of fetal malformation with nervous system,urinary system,cleft lip/palate,congenital heart defect and digestive system were detected,occupying the first five highest incidence,and a total of 18 misdiagnosis took place,among which olydactyl,anal atresia and ear deformities share a higher misdiagnosis rate.The most proper time for a screening in fetal malformation was during 20-24th week pregnant.And an ultrasound examine during 32-36th weeks was also proved to be necessary for some diseases.Conclusion The condition of all parts and all organs of fetuses can be observed with color Doppler ultrasound in real-time with