重型颅脑损伤早期肠内营养支持的临床研究

目的 探讨颅脑损伤后早期肠内营养支持疗法的特点。方法 对40例经临床或CT证实为重型颅脑损伤病例随机分为两组，分别早期给予肠内营养（early enteral feeding,EEF)与肠外营养（total parenteral untrition,TPN)，在摄入同等热量、同等氮量的条件下，对两组有关临床数据进行比较。结果 EEF组24小时排氮量明显少于TPN组，氮平衡，肌酐身高指数（ICr)等营养指标优于TPN组。伤后28天，EEF组体重丢失显著少于TPN组，GCS评分较TPN组显著改善。结论 EEF可维持胃肠道粘膜结构的完整性，促进消化吸收功能的恢复，减轻伤后分解代谢，促进营养和意识状态的改善。

Clinical study of early enteral feeding in severe head injury

Objective To discuss the advantage of early enteral feeding in severe head injury.?Methods Forty cases were divided randomly into two groups,early enteral feeding group(EEF) and total parenteral nutrition group(TPN),each of which equal quantity of heat and nitrogen had been given.?Results Twenty forty hours quantity of nitrogen excreted was less obviously in the EEF than that in the TPN.EEF is superior to TPN in nitrogen balance,index of creatinine and stature(ICr),etc.Twenty eight days after injury,weight loss of the EEF was less apparently than that of the TPN group.GCS were better in EEF than that in the TPN.?Conclusion EEF can maintain integrality of gastrointestinal mucosa,help to recover digestive and absorptive function,moderate post traumatic catabolism,and improve nourishment and consciousness.