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原卟啉钠治疗高胆红质血症67例
引用本文:严幼卿,沈承玲,徐萍,丁正炜,曹玉莲. 原卟啉钠治疗高胆红质血症67例[J]. 中国新药与临床杂志, 1986, 0(3)
作者姓名:严幼卿  沈承玲  徐萍  丁正炜  曹玉莲
作者单位:上海市上海县结核病防治院传染科,上海市上海县结核病防治院传染科,上海市上海县结核病防治院传染科,上海市上海县结核病防治院传染科,上海市上海县结核病防治院传染科 上海 201103,上海 201103,上海 201103,上海 201103,上海 201103
摘    要:以原卟啉20 mg tid口服治疗病毒性肝炎所致高胆红质血症患者67例,并以国内常用利胆退黄中草药治疗43例作为对照组。治疗后原卟啉钠对降低胆红质、锌浊度、谷丙转氨酶疗效显著,分别达97%,100%,98%,高于中草药组(p<0.01),并对尿液的粪卟啉转阴性也有显著疗效。原卟啉钠除个别病人有药物热以外,未见其他副作用,安全范围大,值得进一步推广使用。

关 键 词:原卟啉钠  高胆红质血症  粪卟啉  中草药

Treatment of 67 hyperbiliirubinemia patients with protoporphyrin sodium
YAN You-qing,SHEN Chen-lin,XU Ping,DING Zheng-wei,CAO Yu-lian. Treatment of 67 hyperbiliirubinemia patients with protoporphyrin sodium[J]. Chinese Journal of New Drugs and Clinical Remedies, 1986, 0(3)
Authors:YAN You-qing  SHEN Chen-lin  XU Ping  DING Zheng-wei  CAO Yu-lian
Abstract:Protoporphyrin sodium 20 mg tid po to 67 patients with hyperbili-rubinemia caused by hepatitis.lt reduced serum bilirubin 97%, zinc turbidity 100 %,and serum GPT 98% (p<0.01). Por-phyrins disappeared in urine and feces. There were few side reactions except fever in 1 patient.Traditional Chinese medicines were given to 43 patients for comparison.Which reduced serum bilirubin 84%, zinc turbidity 46%, and serum GPT 63%?It is suggested that protoporphyrin sodium is worthy of further clinical trials.
Keywords:Protoporphyrins  hy-perbilirubinemia  porphyrins in excreta  herbal medicine
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