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大鼠肝脏胰腺十二指肠整块联合异位移植
引用本文:孟令忠,钟守先,乔海泉,肖毅.大鼠肝脏胰腺十二指肠整块联合异位移植[J].中华器官移植杂志,1998,19(4):211-213.
作者姓名:孟令忠  钟守先  乔海泉  肖毅
作者单位:1. 中国协和医科大学追加训练班,北京,100730
2. 北京协和医院基本外科
3. 哈尔滨医科大学附一院普外科
摘    要:为探索肝胰十二指肠整块联合移植术式的可行性,在国内首先建立了大鼠SHPD模型,并评价了术后大鼠生存以及移植物功能状况。结果表明大鼠异位SHPD切实可行,手术成功率高,术后1周存活率达75%,能长期存活,术后行相关检查,表明移植物血管通畅,供肝和供胰有功能。

关 键 词:肝脏  胰腺  十二指肠  联合移植  异位移植

Simultaneous en bloc liver, pancreas, and duodenum heterotopic transplantation in rats
Meng Lingzhong,Zhong Shouxian,Qiao Haiquan,et al..Simultaneous en bloc liver, pancreas, and duodenum heterotopic transplantation in rats[J].Chinese Journal of Organ Transplantation,1998,19(4):211-213.
Authors:Meng Lingzhong  Zhong Shouxian  Qiao Haiquan  
Abstract:In order to study the operation feasibility of heterotopic simultaneous en bloc liver, pancreas, and duodenum transplantation (SHPD), the SHPD model in rats was established for the frist time in China, the status of rat survival and graft function evaluated postoperatively. The results revealed that the rat SHPD model was feasible, with the operative successful rate being 76.9% , oneweek postoperative survival rate being 75%, long survival time without complications being more than 3 months, and good function of the grafted liver and pancreas. In addition, SHPD model is suitable for the experimental study of transplantation immunology, hepatotrophism, etc, and enlightens the treatment of some benign liver diseases with or withour type 1 diabetes mellitus.
Keywords:Liver  Pancreas  Duodenum    Combined transplantation  
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