| Ethical tensions in solid organ transplantation： The price of success |
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| 引用本文： | Kulkarni S,Cronin DC. Ethical tensions in solid organ transplantation： The price of success[J]. World journal of gastroenterology : WJG, 2006, 12(20): 3259-3264. DOI: 10.3748/wjg.v12.i20.3259 |
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| 作者姓名： | Kulkarni S Cronin DC |
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| 作者单位： | Department of Surgery Yale University School of Medicine Tompkins 202,333 Cedar Street,New Haven,CT 06520,United States,Director Liver Transplantation,Director Transplant Intensive Care Unit,Yale-New Haven Hospital,Greenwall Faculty Scholar,Yale University School of Medicine,Tompkins 202,333 Cedar Street,New Haven,CT 06520,United States |
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| 摘 要： | Solid organ transplantation has rapidly developed into the therapy a choice for end-stage organ failure. The expansion of its use has resulted is a large deficiency in organ supply. To address this, the field of organ transplantation has attempted to develop new strategies that would increase the availability of organs for transplant. Some of these strategies include expansion of the donor pool by increasing the number of living donors or using deceased donor organs that may be marginal or "expanded". The intent is to bring life-saving therapy to individuals in need; however, much of this expansion has been brought forward without clear prospective guidelines. This article focuses on the current disparity between organ supply and demand, and how this has impacted the use of living donors and development of the "expanded donor" concept.
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| 关 键 词： | 器官移植 临床表现 病理机制 治疗 |
| 收稿时间： | 2006-03-29 |
Ethical tensions in solid organ transplantation: the price of success |
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| Kulkarni Sanjay,Cronin David-C. Ethical tensions in solid organ transplantation: the price of success[J]. World journal of gastroenterology : WJG, 2006, 12(20): 3259-3264. DOI: 10.3748/wjg.v12.i20.3259 |
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| Authors: | Kulkarni Sanjay Cronin David-C |
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| Affiliation: | 1. Department of Surgery, Yale University School of Medicine, Tompkins 202, 333 Cedar Street, New Haven, CT 06520, United States
2. Director Transplant Intensive Care Unit, Yale-New Haven Hospital,Greenwall Faculty Scholar, Yale University School of Medicine,Tompkins 202, 333 Cedar Street, New Haven, CT 06520,United States |
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| Abstract: | Solid organ transplantation has rapidly developed into the therapy a choice for end-stage organ failure. The expansion of its use has resulted is a large deficiency in organ supply. To address this, the field of organ transplantation has attempted to develop new strategies that would increase the availability of organs for transplant. Some of these strategies include expansion of the donor pool by increasing the number of living donors or using deceased donor organs that may be marginal or "expanded". The intent is to bring life-saving therapy to individuals in need; however, much of this expansion has been brought forward without clear prospective guidelines. This article focuses on the current disparity between organ supply and demand, and how this has impacted the use of living donors and development of the "expanded donor" concept. |
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| Keywords: | Ethical tensions Organ transplantation Donor |
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