| 海藻硫酸多糖对小鼠免疫功能的调节作用 |
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| 引用本文： | 刘志辉, 孟庆勇, 刘秋英, 郑辉. 海藻多糖对γ射线照射小鼠免疫功能的影响[J]. 中国公共卫生, 2003, 19(2): 171-172. |
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| 作者姓名： | 刘志辉 孟庆勇 刘秋英 郑辉 |
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| 作者单位： | 1.广东医学院分析中心, 湛江 524023;2.暨南大学医学院生理教研室 |
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| 基金项目： | 广东省湛江市科技重点攻关项目 |
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| 摘 要： | ttttt 目的 ttttt观察海藻多糖对辐射损伤小鼠免疫功能的影响。ttttt 方法 ttttt测定小鼠胸腺细胞自发掺入3H-TdR的能力、脾细胞对ConA(刀豆蛋白A)及LPS(脂多糖)的增殖反应及脾混合淋巴细胞反应, 考察海藻多糖对γ射线照射小鼠免疫功能的影响。ttttt 结果 ttttt海藻多糖处理组小鼠胸腺细胞自发掺入3H-TdR值、脾细胞对ConA及LPS的增殖反应、脾混合淋巴细胞反应均较照射组明显增强(P < 0.05), 且与海藻多糖的剂量增加呈正相关。ttttt 结论 ttttt海藻多糖对辐射所致的免疫功能损伤有明显的保护作用。
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| 关 键 词： | 海藻多糖 免疫功能 辐射损伤 辐射防护 |
| 收稿时间： | 2002-03-25 |
An titumor activity and immunological properties of marine algal polysaccharides,especially fucoidan,prepared from Sargassum thunbergii of Phaeophyceae |
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| LIU Zhi-hui, MENG Qing-yong, LIU Qiu-ying, . Influence of marine algal polysaccharide on immune function of γ ray irradiated mice[J]. Chinese Journal of Public Health, 2003, 19(2): 171-172. |
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| Authors: | LIU Zhi-hui MENG Qing-yong LIU Qiu-ying |
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| Affiliation: | 1.Analysis Center of Guangdong Medical College (Zhanjiang 524023, China) |
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| Abstract: | ttttt Objective tttttTo observe the effect of marine algal polysaccharide on immune function of irradiated mice.ttttt Methods tttttThe spontaneous incorporation of 3H-TdR into thymocytes, proliferation response of splenocytes to ConA and LPS and mixed lymphocyte reaction was examined.ttttt Results tttttMarine algal polysaccharide could enhance spontaneous incorporation of 3H-TdR into thymocytes, accelerate the proliferation of T and B lymphocytes and increase the abilities of mixed lymphocyte reaction.ttttt Conclusion tttttMarine algal polysaccharide had significant effect on protecting immune function from irradiation injuries. |
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| Keywords: | marine algal polysaccharide immune function radiation damage radiation protection |
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