胰管结石的临床特点及外科处理

目的探讨胰管结石的临床特点及外科处理方法。方法回顾性分析1990年至2008年手术治疗25例胰管结石的临床资料。结果25例均有上腹痛，合并Ⅱ型糖尿病8例，脂肪泻5例，阻塞性黄疸2例，胰头癌1例，6例有急性胰腺炎发作史，均采用影像学检查方法（B超、腹部X线平片、CT、内镜逆行胰胆管造影、磁共振胰胆管造影）确诊。行胰管切开取石、胰管空肠侧侧Roux—en—Y吻合术20例，胰体尾切除、胰断端套入空肠端Roux—en—Y吻合术4例，胰十二指肠切除术1例，无手术并发症。术后25例随访2个月～4年，上腹痛症状20例术后消失，5例减轻。8例合并糖尿病者，4例血糖恢复正常。5例合并脂肪泻者，2例脂肪泻消失，1例减轻。结论影像学检查是确诊胰管结石的主要方法。胰管切开取石、胰管空肠侧侧Roux-en—Y吻合术为治疗胰管结石的主要术式。

Clinical characteristics and surgical treatment of pancreatic duct stone

Objective To explore clinical characteristics and surgical treatment of pancreatic duct stone.Methods Clinical data of 25 cases pancreatic duct stone undergoing operation from 1990 to 2008 were retrospectively analyzed. Results All of the 25 cases suffered upper abdominal pain, among whom 8 cases were concomitant with type 2 diabetes mellitus, 5 with steatorrhea, 2 with obstructive jaundice, 1 with pancreatic head cancer and 6 with acute pancreatitis recurrence history. All cases were confirmed by imaging diagnosis, such as ultrasonography, abdominal X-ray film, CT, endoscopic retrograde cholangiopancreatography and magnetic resonance cholangiopancreatography. 20 cases underwent pancreolithotomy with Roux-en-Y side-to-side pancreaticojejunostomy. 4 cases underwent body-tail pancreatectomy with pancreatojejunostomy and 1 case underwent pancreatoduodenectomy. No complication was found. 25 cases were followed for 2 months to 4 years after operation. Among all 25 cases with upper abdominal pain, 20 cases got rid of the symptoms and 5 cases were relieved postoperatively.Among 8 cases with diabetes mellitus, 4 cases resumed normal blood glucose postoperatively. Among 5 cases with steatorrhea, steatorrhea disappeared in 2 cases and 1 case were alleviated postoperatively. Conclusions Imaging examinations are the main diagnostic methods for pancreatic duct stone. Pancreolithotomy and Roux-en-Y side-toside pancreaticojejunostomy are effective operative techniques.