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经门静脉胰岛移植后移植物的早期丢失
引用本文:所广军,赵中辛. 经门静脉胰岛移植后移植物的早期丢失[J]. 国际外科学杂志, 2009, 36(11). DOI: 10.3760/cma.j.issn.1673-4203.2009.11.012
作者姓名:所广军  赵中辛
作者单位:同济大学附属东方医院普外科,上海,200120;同济大学附属东方医院普外科,上海,200120
摘    要:经门静脉胰岛移植是目前治疗Ⅰ型糖尿病最有效的治疗方法.然而有高达70%的胰岛移植物在移植后2周内被破坏,只有少部分植入的胰岛在肝脏内定植后发挥作用,这导致了胰岛移植效果的不佳.本文对引起这一早期胰岛移植物丢失的原因及其应对措施予以综述.

关 键 词:胰岛移植  门静脉移植  移植物丢失

The early loss of intraportally transplanted islets
SUO Guang-Jun,ZHAO Zhong-Xin. The early loss of intraportally transplanted islets[J]. International Journal of Surgery, 2009, 36(11). DOI: 10.3760/cma.j.issn.1673-4203.2009.11.012
Authors:SUO Guang-Jun  ZHAO Zhong-Xin
Abstract:The intraportal islet transplantation is the most hopeful method for the treatment of type 1 dia-betes mellitus. However about 70% of transplanted islets would be destroyed in the early two weeks after transplantation, only a few parts of them could engraft in liver and become functional. This results in the lower efficiency of islet transplantation. Here we review the reasons of this early islet loss and its preventive strategies.
Keywords:islet transplantation  intraportal transplantation  graft loss
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