Affiliation: | 1. Clinical Effectiveness Unit, The Royal College of Surgeons of England, , London, UK;2. Clinical Trials and Evaluation Unit, Bristol Heart Institute, University of Bristol, , Bristol, UK;3. Papworth Hospital NHS Trust, , Papworth Everard, UK;4. Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, , Newcastle, UK;5. NHS Blood and Transplant, , Bristol, UK;6. Wythenshawe Hospital NHS Trust, , Manchester, UK;7. Royal Brompton and Harefield NHS Foundation Trust, Harefield Hospital, , Harefield, Middlesex, UB9 6JH UK;8. Imperial College, Institute of Cardiovascular Medicine and Science, National Heart and Lung Institute, , London, SW3 6LY UK |