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Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III
Authors:Kent D. Taylor  Xiuqing Guo  Linda M. Zangwill  Jeffrey M. Liebmann  Christopher A. Girkin  Robert M. Feldman  Harvey Dubiner  Yang Hai  Brian C. Samuels  Joseph F. Panarelli  John P. Mitchell  Lama A. Al-Aswad  Sung Chul Park  Celso Tello  Jeremy Cotliar  Rajendra Bansal  Paul A. Sidoti  George A. Cioffi  Robert N. Weinreb
Affiliation:1. Institute for Translational Genomics and Population Sciences and Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California;2. Department of Ophthalmology, Hamilton Glaucoma Center, Shiley Eye Institute, University of California, San Diego, La Jolla, California;3. Bernard and Shirlee Brown Glaucoma Research Laboratory, Harkness Eye Institute, Columbia University Medical Center, New York, New York;4. Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama;5. Ruiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas;6. Eye Care Center Management, Inc., Marrow, Georgia;7. Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York;8. Center for Public Health Genomics, Wake Forest School of Medicine, Winston-Salem, North Carolina;9. Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina;10. Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina;11. Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina;12. Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina;13. Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina
Abstract:
Keywords:AD  African descent  ADAGES  African Descent and Glaucoma Evaluation Study  AMR  African subjects from the Thousand Genomes Project  ASW  African American subjects from the Thousand Genomes Project  AUC  area under the receiver operating characteristic curve  dbGENE  database of gene information in the National Center for Biotechnology Information  dbSNP  database of single nucleotide polymorphism information in the National Center for Biotechnology Information  ED  European descent  KEGG  Kyoto Encyclopedia of Genes and Genomes  GWAS  genome-wide association study  LD  linkage disequilibrium  MAF  minor allele frequency  OMIM  Online Mendelian Inheritance in Man  POAG  primary open-angle glaucoma  ROC  receiver operating characteristic  SNP  single nucleotide polymorphism  WFSM  Wake Forest School of Medicine
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