Specific Features of the Immune Response in Old Recipient Mice to Cell Therapy

Implantation of somatic cells from autopsy specimens (15-18 weeks gestation) had a modulatory effect on immunogenesis in old mice. Activation of the immune system in recipient animals after administration of somatic cells reflects a multistage influence of test preparation. The observed changes were reversible. A progressive decrease in activation of the immune system in recipient mice was not accompanied by the development of pathological changes. Repeated implantation was required to maintain these processes. Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 1, pp. 48-51, 2009