Management of third-trimester diabetic pregnancies with the use of continuous subcutaneous insulin infusion therapy: A pilot study |
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Authors: | Roger H Hertz Katherine C King Satish C Kalhan |
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Institution: | 1. Department of Obstetrics and Gynecology, Case Western Reserve University at Cleveland Metropolitan General Hospital Cleveland, OhioUSA.;2. Department of Pediatrics, Case Western Reserve University at Cleveland Metropolitan General Hospital Cleveland, OhioUSA. |
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Abstract: | Six women with juvenile-onset diabetes were managed as outpatients during the third trimester of pregnancy with continuous subcutaneous insulin infusion therapy. Twenty-four-hour metabolic profiles for plasma glucose, β-hydroxybutyrate, and triglycerides were monitored prior to, 1 week, 5 weeks, and 10 weeks after initiation of continuous subcutaneous insulin infusion therapy and compared with the metabolic profiles of 10 normal (nondiabetic) pregnant women. Near-normal metabolic profiles were achieved in these patients after 5 weeks of therapy in this pilot study. Patient motivation, compliance, and understanding of their illness were crucial in achieving the therapeutic goals of normoglycemia. |
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Keywords: | Reprint requests: Roger H Hertz M D Department of Obstetrics and Gynecology Cleveland Metropolitan General Hospital 3395 Scranton Road Cleveland OH 44109 |
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