Two new compounds from the fruiting bodies of Ganoderma philippii |
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| Authors: | Shuang Yang Qing-Yun Ma Fan-Dong Kong Qing-Yi Xie Sheng-Zhuo Huang Li-Man Zhou |
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| Institution: | 1. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China;2. College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China |
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| Abstract: | Two new compounds, philippin (1) and 3β,9α,14α-trihydroxy-(22E,24R)-ergost-22-en-7-one (2), were isolated from the fruiting bodies of Ganoderma philippii. Their structures were elucidated on the basis of the spectroscopic technologies, including 1D and 2D NMR as well as MS. The bioassay of inhibitory activity against acetylcholinesterase (AChE) showed compound 1 exhibited weak inhibitory activity against AChE. |
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| Keywords: | Ganodermataceae Ganoderma philippii philippin ergost AChE inhibitory activity |
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