Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra |
| |
| Authors: | Xiao Hu Mei-Hua Yu Gui-Rui Yan He-Yao Wang Ai-Jun Hou |
| |
| Affiliation: | 1. Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 201203, China;2. Innovation Center of Chinese Medicine, China State Institute of Pharmaceutical Industry, Shanghai 201203, China;3. Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, China |
| |
| Abstract: | A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2–4) and five known Diels–Alder adducts (5–9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sanggenon C (8), and sanggenon O (9) showed significant inhibitory effects on mushroom tyrosinase. |
| |
| Keywords: | Morus nigra Moraceae isoprenylated phenolic compounds nigrasin K mushroom tyrosinase |
|
|
