| 乙型及丙型肝炎病毒感染与原发性肝癌的临床研究 |
| |
| 引用本文： | 刘利波,冯军,张娟,李晓军.乙型及丙型肝炎病毒感染与原发性肝癌的临床研究[J].胃肠病学和肝病学杂志,2011,20(4):338-340. |
| |
| 作者姓名： | 刘利波 冯军 张娟 李晓军 |
| |
| 作者单位： | 1. 中国人民解放军第266医院消化科,河北,承德,067000
2. 承德市中心医院 |
| |
| 摘 要： | 目的研究HBV DNA、HBsAg、HBeAg、HBeAb、HBcAb及抗-HCV与原发性肝癌发生的相关性。方法采用回顾性调查分析方法,对58例原发性肝癌患者（病例组）,同期收治的58例其他恶性肿瘤患者（对照组）HBV和HCV感染情况进行统计,并分析HBV血清标志物及HBV DNA与原发性肝癌发生发展的规律。结果两组资料的HBV感染率分别为82.76%和44.83%,病例组与对照组比较有显著性差异（P〈0.05）,单纯HCV感染及HBV/HCV混合感染率两组无明显差异（P〉0.05）;血清HBV DNA阳性率在病例组和对照组分别为72.92%、23.08%（P〈0.05）;HBsAg、HBeAb和HBcAb检出率病例组高于对照组（P〈0.05）;而HBeAg阳性率两组比较无显著性差异（P〉0.05）。结论在慢性HBV感染的肝癌高发人群中,HBV DNA、HBsAg、HBeAg、HBeAb及HBcAb所反映的HBV感染状态及不同临床演变过程与肝癌的发生发展密切相关,共同参与肝癌的发病机制。
|
| 关 键 词： | 乙型肝炎病毒 丙型肝炎病毒 HBV DNA 乙型肝炎血清标志物 原发性肝癌 |
Association of HBV, HCV with primary liver cancer |
| |
| LIU Libo,FENG Jun,ZHANG Juan,LI Xiaojun.Association of HBV, HCV with primary liver cancer[J].Chinese Journal of Gastroenterology and Hepatology,2011,20(4):338-340. |
| |
| Authors: | LIU Libo FENG Jun ZHANG Juan LI Xiaojun |
| |
| Institution: | LIU Libo1,FENG Jun2,ZHANG Juan1,LI Xiaojun1 1.Department of Gastroenterology,Chinese PLA 266 Hospital,Chengde 067000,2.Chengde Central Hospital,China |
| |
| Abstract: | Objective To investigate the correlation of HBV DNA,HBsAg,HBeAg,HBeAb,HBcAb,anti-HCV with primary liver cancer(PLC).Methods The infection of HBV and HCV among 58 patients with PLC(case group) and 58 patients with other cancers(control group) was analyzed and the relationship of serum HBV markers and HBV DNA with PLC was investigated by retrospective study.Results The positive rate of HBV in case group was 82.76%,and the control group 44.83%.There was a significant difference between the two groups(P<0.05).T... |
| |
| Keywords: | HBV DNA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
