周剂量紫杉醇同步后程加速超分割放疗治疗93例食管癌的临床研究 |
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引用本文: | 马胜禄,陈利辉,刘向军,谢朝辉.周剂量紫杉醇同步后程加速超分割放疗治疗93例食管癌的临床研究[J].河北医学,2011,17(6):714-717. |
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作者姓名: | 马胜禄 陈利辉 刘向军 谢朝辉 |
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作者单位: | 1. 河北省滦平县世济医院,河北,滦平,068250 2. 河北省滦平县医院,河北,滦平,068250 3. 河北省承德市肿瘤医院,河北,承德,067000 |
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基金项目: | 河北省承德市科研指导计划项目 |
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摘 要: | 目的:观察放射治疗配合紫杉醇化疗对食管癌的临床疗效.方法:对173例食管癌病人根据不同的治疗方法分为两组:单纯放射治疗组(单放组)和放射治疗同步化疗组(放化疗组).单放组80例,采用常规设野放疗,DT65-70 Gy;放化疗组93例,放疗方法及剂量同单放组,化疗采用紫杉醇每周同步方案.两组均随访2年.结果:局部近期疗效...
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关 键 词: | 食管癌 化疗后程加速超分割放疗 紫杉醇 |
Study on Late Course Accelerated Fractionated Irradiation Combined with Concurrent Chemotherapy for 93 Cases Esophagus Squamous Cell Carcinoma |
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Institution: | MA Shenglu,et al(Shiji Hospital of Luanping County,Hebei Luanping068250,China) |
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Abstract: | Objective:To study the effect of radiotherapy combined with paclitaxel chemotherapy on esophageal cancer.Method:173 cases of esophageal cancer were divided into conventional radiotherapy(80 cases) to a total of 65-70 Gy;combined group with received the same radiotherapy as simple irradiation group plus chemotherapy with weekly paclitaxel.Both groups were followed up for 2 years.Result:The short-term results of radiotherapy combined with chemotherapy was better than that of radiotherapy alone.The difference between these two groups was statistically(P〈0.05).The one and two years survival rate were 87%,68.8% in combined.survival rate were 51.3%,32.5% in simple irradiation group.The survival rates in the combined group were thus much better than those in simple irradiation group(P〈0.05).Conclusion:Radiotherapy combined with chemotherapy for advanced esophageal cancer is effective and merits further study in the clinic. |
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Keywords: | Esophageal neoplasms Radiotherapy Paclitaxel |
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