| Affiliation: | (1) Serviço de Biologia Forense, Instituto Nacional de Medicina Legal, Coimbra, Portugal;(2) Instituto Nacional de Toxicología y Ciencias Forenses, M° de Justicia, Madrid, Spain;(3) IPATIMUP, Rua Dr. Roberto Frias, s/n, 4200-465 Oporto, Portugal;(4) Faculdade de Ciências, Universidade do Porto, Oporto, Portugal;(5) Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal |
| Abstract: | In a genetic study of unrelated donors from Bahia (Brazil), one sample contained a 16 Y-STR haplotype with double peaks at three loci: DYS389 II, DYS437 and DYS439. The son of the subject had the same haplotype as found in the father. This profile was compared with a similar case found in a paternity case investigation in Madrid (Spain) and a match was found for the full 16 Y-STR haplotype. Because these three loci are located within the AZFa segment, these results are in accordance with duplication of the AZFa region that includes also other Y-STRs currently used in forensic investigation, for example DYS389I and DYS438. This case attracts our attention in the forensic interpretation of Y-haplotype profiles, because multiple alleles at various loci do not indicate forcibly that the sample under analysis is a mixture. |
