经皮肾囊穿刺封闭术治疗难治性肾病综合征临床研究

目的　探讨介入疗法对难治性肾病综合征 (RNS)的疗效。方法　将 6 4例RNS随机分为A ,B两组 ,A组 32例 ,经皮肾囊穿刺向每一肾脂肪囊 (肾囊 )内注入 2 %利多卡因 ,每周 2次 ,同时口服强的松、洛汀新、潘生丁等治疗 ,B组 32例 ,应用强的松、洛汀新、潘生丁等治疗。结果　A组总有效率为 84 .4 % ,B组为 6 5 .6 % ,两组比较 (P <0 .0 5 ) ,A组 1年内复发率低 ,为 2 9.6 % ,B组为 71.4 % ,比较两组 (P <0 .0 1)。结论　利多卡因经皮肾囊内穿刺注射封闭疗法是目前治疗RNS最有效的方法之一 ,值得临床进一步的推广应用。

The Study of Percutaneous Close Renal Adipose Capsula to Treat the Patients with Resistant Nephrotic Syndrome

Objective To investigate the clinical effect on patients with resistant nephrotic syndrome(RNS) treated by interventional therapy.Methods Sixty-four cases with RNS were randomly divided into group A and group B,thirty-two cases with RNS(group A) were injected with 2%lidocaine into each renal adipose capsula percutanous,two times/w,while,they were treated with prednisolone,lotensin,persantin,et al.Thirty-two case with RNS (group B) were treated with prednisolone,lotensin,persantin.Results The response rate in group A were 84.4%,and in group B were 65.5% (P<0.05),the recurrent rate in group A were 29.6% one year.and ingroup B were 71.4% one year(P<0.01).Conclusion It is that the pations with RNS is injectied with lidocaine into renal adipose capsulapercu taneous,is mose of the features.