血清前列腺特异性抗原检测在慢性前列腺炎分型中的临床意义探讨

目的 观察血清前列腺特异性抗原(PSA)在慢性前列腺炎分型中的检测结果,总结其临床意义.方法 选取我院2009年5月至2011年5月68例慢性前列腺炎的患者,设为观察组,参考美国国立卫生研究院(NIH)的分类标准进行分类,分为观察组A(Ⅱ型)21例,观察组B(Ⅲa型)30例,观察组C(Ⅲb型)17例；再选取同期体检健康的人群68例,作为对照组,分别进行血清前列腺特异性抗原检测,观察比较四组受检者PSA水平及观察组不同类型在治疗前后的PSA变化.结果 观察组和对照组的PSA水平比较存在明显差异,观察组的PSA水平明显升高,其中以观察组A升高水平最高(P＜0.05),差异具有统计学意义；观察组治疗前后的PSA水平比较存在明显差异,观察组A治疗后的PSA水平明显下降(P＜0.05),差异具有统计学意义,观察组B、C治疗前后PSA水平差异无显著性(P＞0.05).结论 PSA应用在慢性前列腺分型检测中有一点的指导意义,能够辅助指导临床进行合理分型治疗,但具体对PSA值进行准确的分型界定,仍需进一步研究探讨.

Detection of prostate specific antigen for typing of chronic prostatitis and its clinical significance

ObJective To observe the detection results of serum prostate specific antigen （ PSA ） for typing of chronic prostatitis, and to summarize its clinical significance. Methods In our hospital from May 2009 to May 2011,68 patients with chronic prostatitis, with reference to the United States National Institutes of Health （ NIH ） classification criteria, were included in the study group 21 were assigned to group A II type ）, 30 to group B （ IIIa type ）, and 17 to group C （ II Ib type ）. 68 healthy people were enrolled as control. Serum levels of prostate specific antigen were compared between the four groups, and changes in PSA levels in different types of the study were also observed after treatment. Results In the study group and the control group, PSA level had an obvious difference, it significantly elevated in the study group, the highest level in group A increased （ P〈 0.05 ）, with a statistical significance the observation group before and after treatment with PSA level differences, were observed in group A after treatment with PSA levels were significantly decreased （ P〈 0.05 ）, with a statistical significance PSA level had no significant difference in groups B and C before and after treatment （ P〉 0.05 ）. Conclusions PSA in the typing of chronic prostate hyperplasia has a little significance of guidance. It can help guide logical clinical typing, but the specific values of PSA for accurate classification still need to be further studied.