内镜下不同止血措施对非静脉曲张性上消化道出血的疗效对比

目的]比较内镜下不同止血措施对非静脉曲张性上消化道出血的治疗效果,探讨其临床治疗意义.方法]选取2009年9月-2011年9月在我科治疗的140例非静脉曲张性上消化道出血患者,按照治疗方法分为局部喷洒/注射药物组50例,氨气刀组50例,金属钛夹组40例,比较三组患者的临床首次止血,再出血,住院时间的参数.结果]氩气刀组及金属钛夹组首次止血明显高于局部喷洒/注射药物组(P＜0.05);金属钛夹组再出血低于其他两组(P＜0.05),氩气刀组与局部喷洒/注射药物组首次再出血差异无显著性(P＞0.05);氩气刀组及金属钛夹组有效止血明显高于局部注射药物组(P＜0.05).三组患者住院时间差异无显著性(P＞0.05).结论]三种治疗方法均有其特点,临床治疗非静脉曲张性上消化道出血应根据病变的范围、特点,选取有效的治疗方式.

Comparative study on curative effects of different endoscopic interventions on acute nonvariceal upper gastrointestinal bleeding

Objective To compare the therapeutic effects of different endoscopic interventions on acute nonvariceal upper gastrointestinal bleeding （ANUGB）. Methods 140 patients in our department from September 2009 to September 2011 were selected. These patients were divided into three groups depending on different endoscopic interventions, 50 patients in local spray/injection adrenalin group, 50 in argon plasma coagulation （APC） group and 40 in endoscopic titanium clips （ETC） group. The clinical effects in 3 groups were analyzed and compared. Results APC group and ETC group had higher rate of initial hemostasis than that in local spray/injection adrenalin group （P〈 0.05）. The rebleeding rate in ETC group was significantly lower than those in other two groups （P〈 0.05）. APC group and ETC group had better effective rate of hemostasis （P 〈 0.05）. There were no significant differences in hospital stay in three groups （P 〉 0.05）. Gonclusion There are different characteristics in 3 therapeutic endoscopic interventions. We should choose appropriate endoscopic intervention to treat ANUGB.