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免疫组织化学显微图像分析技术进展
引用本文:司京玉,聂生东,陈瑛,黄永锋,顾顺德,章鲁. 免疫组织化学显微图像分析技术进展[J]. 国际生物医学工程杂志, 2002, 25(3): 117-121
作者姓名:司京玉  聂生东  陈瑛  黄永锋  顾顺德  章鲁
作者单位:上海第二医科大学计算机教研室,上海,200025
摘    要:免疫组织化学是用特异性抗体显示组织化学成分的重要方法 ,是实验结果以显微图像的形式显示出来。对免疫组化图像的分析方法主要包括人工分析和计算机图像处理分析。前者简便易行 ,对实验的标准化要求不高 ,但无法做精确的量化分析 ;后者在精确性、客观性、分析速度等方面具有巨大优势 ,但目前仍不完善。本文对两种分析技术的应用现状、实验要求及特点进行了综述 ,并指出了计算机图像处理技术已经成为免疫组化显微图像分析技术发展的趋势

关 键 词:免疫组织化学  图像分析  图像处理
文章编号:1001-1110(2002)03-0117-05
修稿时间:2001-12-27

The developments of image analyzing technology in immunohistochemical micrograph
SI Jing yu,NIE Sheng dong,CHEN Ying,HUANG Yong feng,GU Shun de,ZHANG Lu. The developments of image analyzing technology in immunohistochemical micrograph[J]. International Journal of Biomedical Engineering, 2002, 25(3): 117-121
Authors:SI Jing yu  NIE Sheng dong  CHEN Ying  HUANG Yong feng  GU Shun de  ZHANG Lu
Abstract:Immunohistochemistry is an important method displaying chemical ingredients in tissues through particular antibody and it displays experimental results using micrograghs.The analyzing methods to immunohistochemical micrographs mostly include manpower analysis and computer assisted image processing analysis.The former is easy to perform and experimental standardization is required lowly,but accurately quantificational analysis is difficult.The latter has great prepotencies in particularity,objectivity and analyzing speed,but is not enough perfect.The paper reviews the applications,experimental requirements and characters of the two methods and indicates that the latter has been the trend of immunohistochemical micrograph analysis.
Keywords:immunohistochemistry  image analysis  image processing
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