| 在人胎盘条件培养液中白细胞介素2对粒-巨噬系祖细胞生长的影响 |
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| 引用本文： | 吴祥元,梁锦华.在人胎盘条件培养液中白细胞介素2对粒-巨噬系祖细胞生长的影响[J].中山大学学报(医学科学版),1992(2). |
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| 作者姓名： | 吴祥元 梁锦华 |
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| 作者单位： | 中山医科大学附属第三医院血液病研究室
(吴祥元)，中山医科大学附属第三医院血液病研究室(梁锦华) |
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| 摘 要： | 在正常骨髓粒-巨噬系祖细胞(CFU-GM)常规培养体系中加入白细胞介索2(IL-2),所有18例CFU-GM的集落产率明显上升,平均上升46.37％,t=11.152,P<0.001。结果提示IL-2和人胎盘条件培养液(HPCM)之间具有协同作用,但IL-2单独并无刺激CFU-GM生长的作用。
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| 关 键 词： | 白细胞介素2 粒-巨噬系祖细胞 人胎盘条件培养液 |
THE MODULATION OF GRANULO-MACROPHAGE COLONY FORMING UNIT GROWTH BY INTERLEUKIN-2 IN VITRO |
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| Wu Xiangyuan Liang Jinhua.THE MODULATION OF GRANULO-MACROPHAGE COLONY FORMING UNIT GROWTH BY INTERLEUKIN-2 IN VITRO[J].Journal of Sun Yatsen University(Medical Sciences),1992(2). |
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| Authors: | Wu Xiangyuan Liang Jinhua |
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| Abstract: | When interleukin-2 (IL-2) was added to normal bone marrow cells to perform gran-ulo-macrophage colony forming unit (CFU-GM) growth, all 18 specimens showed significant increase in CFU-GM plating efficiency, the incremental mean was 46.37% (t = 11.152,P<0.001). This suggests that IL-2 and human placental condition media (HPCM) acts synergically to form CFU-GM. Contrarily in the absence of HPCM, IL-2 has no stimulating effect on CFU-GM growth. |
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| Keywords: | interleukin-2 granulo-macrophage colony forming unit human pla- cental conditioned medium |
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