| A prospective study of vertical transmission of hepatitis C virus |
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| 引用本文： | SUN De Gui 1,LIU Cai Yun 1,MENG Zong Da 2,SUN Yong De 2,WANG Shu Cong 1,YANG Yu Qi 1,LIANG Zheng Lun 3 and ZHUANG Hui 3. A prospective study of vertical transmission of hepatitis C virus[J]. World journal of gastroenterology : WJG, 1997, 3(2): 111-113. DOI: 10.3748/wjg.v3.i2.111 |
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| 作者姓名： | SUN De Gui 1 LIU Cai Yun 1 MENG Zong Da 2 SUN Yong De 2 WANG Shu Cong 1 YANG Yu Qi 1 LIANG Zheng Lun 3 and ZHUANG Hui 3 |
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| 作者单位： | SUN De Gui 1，LIU Cai Yun 1，MENG Zong Da 2，SUN Yong De 2，WANG Shu Cong 1，YANG Yu Qi 1，LIANG Zheng Lun 3 and ZHUANG Hui 3 |
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| 摘 要： | ＡｐｒｏｓｐｅｃｔｉｖｅｓｔｕｄｙｏｆｖｅｒｔｉｃａｌｔｒａｎｓｍｉｓｓｉｏｎｏｆｈｅｐａｔｉｔｉｓＣｖｉｒｕｓＳＵＮＤｅＧｕｉ１，ＬＩＵＣａｉＹｕｎ１，ＭＥＮＧＺｏｎｇＤａ２，ＳＵＮＹｏｎｇＤｅ２，ＷＡＮＧＳｈｕＣｏｎｇ１，ＹＡＮＧＹｕ...
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| 收稿时间： | 1996-09-20 |
A prospective study of vertical transmission of hepatitis C virus |
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| SUN De Gui ,LIU Cai Yun ,MENG Zong Da ,SUN Yong De ,WANG Shu Cong ,YANG Yu Qi ,LIANG Zheng Lun and ZHUANG Hui. A prospective study of vertical transmission of hepatitis C virus[J]. World journal of gastroenterology : WJG, 1997, 3(2): 111-113. DOI: 10.3748/wjg.v3.i2.111 |
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| Authors: | SUN De Gui LIU Cai Yun MENG Zong Da SUN Yong De WANG Shu Cong YANG Yu Qi LIANG Zheng Lun ZHUANG Hui |
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| Affiliation: | SUN De Gui 1,LIU Cai Yun 1,MENG Zong Da 2,SUN Yong De 2,WANG Shu Cong 1,YANG Yu Qi 1,LIANG Zheng Lun 3 and ZHUANG Hui 3 |
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| Abstract: | AIM To study the mechanism of mother to infant transmission of HCV prospectively. METHODS Using a nested PCR for detection of HCV RNA and the second generation ELISA for detection of anti HCV, 13 pregnant women who surffered from post transfusion hepatitis C(PT HC), and their 15 babies were studied to evaluate mother to infant transmission of HCV. RESULTS The total infection rate of HCV was 86 7% in the babies, including 1 case of clinical HC (7 7%), 3 subclinical HC (23 1%), and 9 inapparent HCV (69 2%). The positive rates of anti HCV and HCV RNA declined with the age of the babies, to 7 7% for anti HCV and 15 4% for HCV RNA at the age of 3 years. CONCLUSION Babies born from mothers infected with HCV were vertically infected by HCV in a high rate, but the consequence was not serious. Four fetuses born to mothers positive of anti HCV and HCV RNA through induced labor were all infected by HCV, suggesting that the mother to infant transmission of HCV mainly occurred in the uterine. |
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| Keywords: | hepatitis C virus RNA viral disease transmission vertical |
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