An autoantibody derived from mice with experimental systemic lupus erythematosus is directed against the essential splicing factor SF53/4 a possible role for large nuclear ribonucleoprotein particles in autoimmune disorders |
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Authors: | Ast, Gil Goldblatt, Drora Waisman, Ari Sperling, Ruth Mozes, Edna Sperling, Joseph |
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Affiliation: | 1 Departments of Organic Chemistry, The Weizmann Institute of Science Rehovot 761100, Israel 2 Chemical Immunology, The Weizmann Institute of Science Rehovot 76100, Israel 3 Department of Genetics, The Hebrew University of Jerusalem Jerusalem 91904, Israel |
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Abstract: | |
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Keywords: | autoimmunity monocional antibodies pre-mRNA splicing RNP particles spliceosome |
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