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An autoantibody derived from mice with experimental systemic lupus erythematosus is directed against the essential splicing factor SF53/4 a possible role for large nuclear ribonucleoprotein particles in autoimmune disorders |
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| Authors: | Ast Gil; Goldblatt Drora; Waisman Ari; Sperling Ruth; Mozes Edna; Sperling Joseph |
| Institution: | 1 Departments of Organic Chemistry, The Weizmann Institute of Science Rehovot 761100, Israel 2 Chemical Immunology, The Weizmann Institute of Science Rehovot 76100, Israel 3 Department of Genetics, The Hebrew University of Jerusalem Jerusalem 91904, Israel |
| Abstract: | |
| Keywords: | autoimmunity monocional antibodies pre-mRNA splicing RNP particles spliceosome |
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