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妊娠高血压综合征患者检测D-二聚体及一氧化氮的临床意义
引用本文:胡恩赑,刘刚,宋尉,张漩.妊娠高血压综合征患者检测D-二聚体及一氧化氮的临床意义[J].淮海医药,2008,26(3):213-214.
作者姓名:胡恩赑  刘刚  宋尉  张漩
作者单位:安徽省蚌埠市第三人民医院,检验科,233000
摘    要:目的探讨妊娠高血压综合征患者D-二聚体及一氧化氮检测的临床意义。方法检测61例妊娠期高血压患者、27例正常晚期妊娠孕妇和30例正常非妊娠妇女D-二聚体及一氧化氮的水平。结果妊娠期高血压患者组血浆D-二聚体水平明显高于正常晚期妊娠组(P〈0.01),血浆D-二聚体水平越高,妊娠期高血压病情越重。妊娠期高血压组血清一氧化氮水平明显低于正常晚期妊娠组(P〈0.01),血清一氧化氨水平与妊娠期高血压严重程度无明显相关性。结论血浆D-二聚体水平升高、血清一氧化氮水平下降与妊娠期高血压综合征发病有关。

关 键 词:高血压  妊娠性  D-二聚体  一氧化氮
文章编号:1008-7044(2008)03-0213-02
修稿时间:2007年9月27日

Clinical significance of detection of D-dimer and nitric oxide in patients with pregnancy-induced hypertension
HU En-bi,LIU Gang,SONG Wei,et al..Clinical significance of detection of D-dimer and nitric oxide in patients with pregnancy-induced hypertension[J].Journal of Huaihai Medicine,2008,26(3):213-214.
Authors:HU En-bi  LIU Gang  SONG Wei  
Institution:HU En-bi , LIU Gang, SONG Wei , et al. ( Department of Clinical Laboratory, The Third Hospital of Bengbu ,Anhui 233000, China )
Abstract:Objective To study the clinical significance of D-dimer and nitric oxide levels in patients with pregnancy-in-duced hypertension(PIH).Methods D-dimer and NO levels of 61 women with PIH,27 normal pregnant women and nonpregnant women were measured.Results D-dimer level in patients with PIH was significantly higher than those in normal pregnant women(P<0.01).The higher D-dimer level is,the more severe PIH is.NO level was significantly lower in patients with PIH than normal pregnant women(P<0.01).There was no obvious correlation between NO level and severeness of PIH.Conclusion The tendency of increased D-dimer level and declined NO level may play a role in the pathogenesis of PIH.
Keywords:Hypertension  pregnant  D-dimer  Nitric oxide
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