急性冠脉综合征病人脑卒中发生率及其预后

目的探讨急性冠脉综合症(ACS)病人合并卒中的危险因素及其预后。方法共2623例ACS住院病人入选,观察基本临床资料和相关事件。结果住院期间51例(1.94%)发生卒中,其中16例(31.37%)死亡,ST段抬高的心肌梗塞组的卒中发病率(3.11%)明显高于不稳定性心绞痛组(1.61%),P<0.05,院内卒中的发生与其它血管事件密切相关,包括心力衰竭、心源性休克、心跳骤停、心房纤颤、急性肾功能衰竭和糖尿病。结论ACS住院病人发生卒中率虽不高但其病死率高达31.37%,对此高危人群应采取个体化治疗措施。

The incidence and prognosis of stroke in patients with acute coronary syndrome

Objective To investigate the risk factors and prognosis of patients with acute coronary syndrome(ACS) associated with stroke.Methods 2623 hospitalized patients with ACS were enrolled for the retrospective analysis.The baseline clinical records and related-events to stroke were studied.Results During in-hospital time,51 patients(1.9%) were found with stroke and 16(31.37%) of the 51 patients died.The incidence of stroke(3.11%) in ST-elevation myocardial infarction was significantly higher than that(1.61%) in unstable angina,P<0.05.The incidence of in-hospital stroke was closely related to other vascular events,including heart failure,cardiac arrest,auricular fibrillation,acute renal failure and diabetes mellitus.Conclusion Although the incidence of stroke in hospitalized patients with ACS is low,the mortality is high,the individualized regimen should be used for treatment of this high risk patients.