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血清和精浆抑制素B在无精子症诊断中的应用研究
引用本文:张卫星,王瑞,李培强. 血清和精浆抑制素B在无精子症诊断中的应用研究[J]. 中华男科学杂志, 2007, 13(7): 598-600
作者姓名:张卫星  王瑞  李培强
作者单位:1. 郑州大学第一附属医院泌尿外科,河南省高等学校临床医学重点学科开放实验室,河南,郑州,450052
2. 郑州大学第三附属医院外科,河南,郑州,450052
摘    要:目的:评价血清和精浆抑制素B浓度在诊断梗阻性和非梗阻性无精子症中的应用价值。方法:测定25例正常生育者(正常对照组),37例梗阻性无精子症以及33例非梗阻性无精子症者的血清卵泡刺激素(FSH)、血清和精浆抑制素B浓度,对无精子症者行睾丸病理Johnsen评分。结果:精浆和血清抑制素B浓度比值在正常对照组和非梗阻性无精子组分别为2.17和3.63,差异无显著性(P=0.29);在梗阻性无精子症组两者比值为0.18,与正常对照组和非梗阻性无精子症组比较显著降低(P<0.01)。结论:精浆和血清抑制素B浓度比值可用于临床诊断梗阻性和非梗阻性无精子症。

关 键 词:抑制素B  无精子症  精浆  血清
文章编号:1009-3591(2007)07-0598-03
收稿时间:2006-09-08
修稿时间:2006-09-082006-12-20

Concentration of Seminal Plasma and Serum Inhibin B: A Predictor in the Diagnosis of Azoospermia
ZHANG Wei-xing,WANG Rui,LI Pei-qiang. Concentration of Seminal Plasma and Serum Inhibin B: A Predictor in the Diagnosis of Azoospermia[J]. National journal of andrology, 2007, 13(7): 598-600
Authors:ZHANG Wei-xing  WANG Rui  LI Pei-qiang
Affiliation:1. Department of Urology, First Affiliated Hospital of Zhengzhou University, Zhengzhou , Henan 450052, China; 2. Department of Surgery, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China
Abstract:Objective: To evaluate the concentrations of seminal plasma and serum inhibin B in the differential diagnosis of obstructive and non-obstructive azoospermia.Methods: We included 37 infertile men with obstructive azoospermia,another 33 with non-obstructive azoospermia and 25 normal fertile men as controls,and measured the concentrations of their FSH serum,seminal plasma and serum inhibin B,using Testicular Histology Johnson Score for the azoospermia infertile men.Results: The concentration ratio of seminal plasma to serum inhibin B was 2.17 in the control and 3.63 in the non-obstructive azoospermia group,with no significant difference(P=0.29) in between,but obviously lower in the obstructive azoospermia group(0.18),significantly different from the above two(P<0.01).Conclusion: The concentration ratio of seminal plasma to serum inhibin B can be used as a predictor in the diagnosis of obstructive and non-obstructive azoospermia.
Keywords:inhibin B   azoospermia   seminal plasma   serum
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