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沈阳地区不同人群HBV感染情况的调查
引用本文:白菡,张琳,马力,刘冬妍,罗青云,赵桂珍,王者虹.沈阳地区不同人群HBV感染情况的调查[J].中国医科大学学报,2006,35(2):181-182.
作者姓名:白菡  张琳  马力  刘冬妍  罗青云  赵桂珍  王者虹
作者单位:1. 中国医科大学附属第二医院感染科,辽宁,沈阳,110004
2. 中国医科大学附属第二医院检验科,辽宁,沈阳,110004
3. 鞍钢曙光医院传染科
摘    要:目的:调查沈阳地区不同人群乙型肝炎病毒(HBV)的感染情况。方法:对6974例在我院住院的病人分为14岁以下、15岁以上和孕妇3组,用ELISA法进行HBV血清学标志物检测,比较各组间HBV的感染情况。结果:14岁以下组HBsAg阳性率明显低于15岁以上组(P〈0.05),乙肝表面抗体(抗-HBS)的阳性率高于15岁以上组,孕妇HBV感染率与普通人群无显著性差异。结论:沈阳地区儿童HBsAg阳性率下降的主要原因可能与乙肝疫苗的广泛接种有关。

关 键 词:乙型肝炎病毒  感染  流行
文章编号:0258-4646(2006)02-0181-02
收稿时间:2005-01-07
修稿时间:2005年1月7日

Investigation on hepatitis B virus infection in different populations of Shenyang city
BAI Han,ZHANG Lin,MA Li,LIU Dong-yan,LUO Qing-yun,ZHAO Gui-zhen,WANG Zhe-hong.Investigation on hepatitis B virus infection in different populations of Shenyang city[J].Journal of China Medical University,2006,35(2):181-182.
Authors:BAI Han  ZHANG Lin  MA Li  LIU Dong-yan  LUO Qing-yun  ZHAO Gui-zhen  WANG Zhe-hong
Institution:1. Department of Infectious Diseases, The Second Affiliated Hospital, China Medical University, Shenyang 110004, China; 2. Clinical Laboratory, The Second Affiliated Hospital, China Medical Unversity; 3. Shuguang Hospital of Anshan Iron and Steel Group Corporation
Abstract:Objective: To investigate hepatitis B virus(HBV) infection in different populations of Shenyang city.Methods:A total of 6974 patients admitted to the hospital were divided into 3 group: group 1(patients aged 14 years and younger),group 2(patients aged 15 years and older),and group 3(pregnant women).HBV serum markers were detected by using enzyme linked immunosorbent assay(ELISA) and compared among 3 groups.Results:The positive rate of HBsAg in group 1 was significantly lower than that in group 2,and the positive rate of anti-HBs in group 1 was significantly higher than that in group 2.No significant difference in HBV infection rate was found between group 2 and group 3.Conclusion:The decrease in the positive rate of HBsAg in children may be the result of universal HBV vaccination.
Keywords:hepatitis B virus  infection  prevalence
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