| 老年高血压病患者血浆心钠素浓度变化与肾素的关系 |
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| 引用本文： | 刘慧霞,孙明,周宏研,韩秀云,王振华.老年高血压病患者血浆心钠素浓度变化与肾素的关系[J].中南大学学报(医学版),1995(2). |
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| 作者姓名： | 刘慧霞 孙明 周宏研 韩秀云 王振华 |
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| 作者单位： | Department of Medicine，Xiangya Hospital，Hunan Medical University |
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| 摘 要： | 检测１００例老年高血压患者（ＥＨＰ）和３０例正常人血浆肾素活性（ＰＲＡ）、心钠素（ＡＮＦ）浓度及左心室重量。结果表明：低肾素性ＥＨＰ血浆ＡＮＦ浓度增高，且与平均动脉压成正相关（ｒ＝０．４６８７，Ｐ＜０．０１），与ＰＲＡ成负相关（ｒ＝－０．４５３６，Ｐ＜０．０１）。伴左心室肥厚的ＥＮＰ血浆ＡＮＦ浓度明显高于Ⅰ期患者（Ｐ＜０．０ｌ），且左心室重量与血浆ＡＮＦ水平成正相关（ｒ＝０．７８９９，Ｐ＜０．０１）。血浆ＡＮＦ水平可作为高血压引起心肌结构，功能早期变化的指标之一。
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| 关 键 词： | 高血压 心钠素 肾素 心肌病，肥大性 老年人 |
PLAsMA ATRIAL NATRIURETIC FACTOR IN ELDERLY HYPEKTENSIVE PATIENTS CORREL ATED
WITH PLAsMA RENIN ACTIVITY |
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| Liu Huixia, Wang Zhenghua, Sun Ming, Zhou
Hohgyen.PLAsMA ATRIAL NATRIURETIC FACTOR IN ELDERLY HYPEKTENSIVE PATIENTS CORREL ATED
WITH PLAsMA RENIN ACTIVITY[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1995(2). |
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| Authors: | Liu Huixia Wang Zhenghua Sun Ming Zhou
Hohgyen |
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| Abstract: | lasma
atrial natriuretic factor(ANF), plasma renin activity(PRA) and left ventricu-lar mass(LVM)were
measured in l00 elderly hypertensive patients(EHP)and 30 nor-motensive control subjects, The
results indicated that in the low renin type EHP, there wasincreased venous plasma ANF
concentration that correlated positively with mean pressure(r=0. 4687,P<0. 01),negatively with
PRA(r=-0. 4536, P<0. 01).The EHP with leftventricular hypertrophy(LVH) had higher plasn1a ANF
Ievels(P<0. 0l) ,a significant posi-tive correlation was observed between plasma ANF Ievels
and LVM(r=0. 7899,P<0. 01)The findings indicated that plasma ANF is one of the marks of LVH
in the essential hyper-tensive patients with LVH. |
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| Keywords: | hypertension atrial natriuretic factor renin cardiomyopathy hyper-trophic aged |
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