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A feasible shortcut for the mobilization outcome: Steady state CD34 positive hematopoietic stem cells
Authors:Yüksel Meltem Kurt  Tekgündüz Emre  S?nmez Cigdem  Topcuoglu Pervin  Yurtcu Arzu  Demiriz It?r  Tetik Ay?egül  Kay?k?? Omür  C?narsoy Murat  Altunta? Fevzi
Institution:Ankara Oncology Research and Education Hospital, Hematology and Stem Cell Transplantation Unit, Ankara, Turkey. meltemkurt@hotmail.com
Abstract:Predicting success of hematopoietic cell mobilization is an important issue for transplant physicians. We examined the steady state peripheral blood CD34+ cell count to predict ability to mobilize adequate hematopoietic progenitor cells in 63 myeloma and lymphoma patients. The median steady state CD34+ cell number was 1.56/μL (0.03-5.76). Although counting steady state CD34+ is definitely cost effective to predict the successful mobilization, we could not find a threshold steady state CD34 count of any value predicting successful mobilization.
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