原发性纵隔畸胎瘤的诊断与外科治疗

目的探讨原发性纵隔畸胎瘤的诊断及外科治疗。方法对1996年3月至2006年3月49例纵隔畸胎瘤患者的临床资料进行回顾性分析。结果结合病史、体格检查、胸片X线、CT、MRI等术前确诊48例。所有患者均行手术治疗,其中完整切除46例,部分切除2例,探查活检1例。术中同时行肺楔形切除8例,部分心包切除6例。无手术死亡及术后并发症发生。术后均经病理证实为畸胎瘤,随访期间无复发病例。结论病史、体格检查与影像学检查是原发性纵隔畸胎瘤的主要诊断手段,手术治疗是有效的治疗方法。早期诊断以及根据肿瘤特点选择合理的手术方式是获得良好治疗效果的关键。

Diagnosis and surgical treatment of the primary mediastinal teratoma

Objective To review the experience of diagnosis and surgical treatment of the primary mediastinal teratomas. Methods The clinical data of forty-nine eases with teratoma were retrospectively analysized from March 1996 to March 2006. Results Based on history, physical examination, chest X-ray, CT scan and magnetic resonance, the diagnosis of forty-eight eases were confirmed before surgery. Surgical procedures were performed in all eases. Forty-six patients were subjected to radical excision ,two patients to partial excision and one patient to exploratory operation. Among all the eases, Wedge resection of the lung was performed in eight cases, partial pericardia excision in six cases. There was no surgically related mortality or complications in any patients. The diagnosis of teratoma was confirmed by postoperative histopathological examination. No relapse occurred during follow-up. Conclusions History, physical examination and radiological imaging are the main diagnostic means for the primary mediastinal teratoma. Surgical resection is an effective therapy. Early diagnosis and correct selection of operation according to the characteristic of the tumor are important to therapy.