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不同血液净化方法对血磷及甲状旁腺素的清除效果研究
引用本文:朱小利,叶玉燕,陈丽萍. 不同血液净化方法对血磷及甲状旁腺素的清除效果研究[J]. 浙江医学, 2008, 30(4): 314-316
作者姓名:朱小利  叶玉燕  陈丽萍
作者单位:金华市人民医院肾内科,321000
摘    要:目的 观察3种不同血液净化方法对维持性血液透析患者血磷及甲状旁腺素(PTH)的清除效果.方法 将36例维持性血液析透患者分为3组,分别采用血液透析滤过(HDF)、血液灌流 血液透析(HP HD)、血液透析(HD)治疗,连续治疗2个月后观察血磷及PTH的变化.结果 HDF组治疗后血磷降至(2.12±0.56)mmol/L,PTH降至(378±168)pg/ml;HP HD组治疗后血磷降至(1.73±0.65)mmol/L,PTH降至(306±157)pg/ml;HD组治疗后血磷降至(1.82±0.61)mmol/L,PTH降至(516±202)pg/ml;3组治疗后血磷及血PTH水平均明显下降(P<0.05).此外,HDF组及HP HD组血磷及PTH清除率均明显大于HD组(P<0.05).结论 HDF及HP HD均能有效清除血磷和PTH,而HD仅能有效清除血磷,不能有效清除PTH.

关 键 词:血液透析滤过  血液灌流  血液透析  血磷  甲状旁腺素  血液透析滤过  净化方法  血磷  甲状旁腺素  清除效果  研究  levels  parathyroid hormone  phosphorus  serum  methods  purification  blood  different  effect  清除率  水平  结果  变化  连续治疗
修稿时间:2007-12-26

Clearance effect of different blood purification methods on serum phosphorus and parathyroid hormone levels
ZHU Xiaoli,YE Yuyan,CHEN Liping. Clearance effect of different blood purification methods on serum phosphorus and parathyroid hormone levels[J]. Zhejiang Medical Journal, 2008, 30(4): 314-316
Authors:ZHU Xiaoli  YE Yuyan  CHEN Liping
Affiliation:ZHU Xiaoli,YE Yuyan,CHEN Liping. Department of Nephrology,Jinhua Municipal People's Hospital,Jinghua 321000,China
Abstract:Objective To compare the clearance effect of different blood purification methods on serum phosphorus and parathyroid hormone (PTH) levels in patients on maintenance hemodialysis. Methods Thirty-six patients on maintenance hemodialysis were randomly divided into three groups:hemodiafiltration group(HDF),hemoperfusion plus hemodialysis group(HP+HD), hemodialysis group(HD). Serum phosphorus and serum PTH levels were observed before and after two month-continuing treatment. Results In HDF group serum phosphoru...
Keywords:Hemodiafiltration Hemoperfusion Hemodialysis Serum phosphorus Parathyroid hormone  
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