| Abstract: | The Centers for Disease Control and Prevention (CDC) revised its guidelines for managing postexposure prophylaxis (PEP) for health care workers who are occupationally exposed to HIV. The CDC did not recommend preventive therapy until 2 years ago, when results from a PEP study indicated that transmission could be reduced by 81 percent, with the use of AZT as the PEP. The new guidelines are straightforward, and recommend a 4-week AZT and 3TC regimen for most common exposures, or an expanded regimen including a protease inhibitor for those at increased risk of transmission. All doctors are urged to consult with experienced physicians regarding the best course of treatment. Rapid HIV testing is also recommended for occupational exposure. Contact information is included for PEP consultation. |
