输血后丙型肝炎感染及影响因素的研究

采用回顾性定群研究方法，对济南市１１９例输血后丙型肝炎感染情况进行了调查。结果表明，１１９例受血者中，抗－ＨＣＶ阳性３１例，阳性率为２６．１％，其中１４例为临床丙型肝炎患者，罹患率为１１．７％。输入经筛检血液的受血者中，ＨＣＶ感染率和丙肝罹患率分别为１４．６％和４．２％，输入未经筛检血液者分别为３３．８％和１６．９％，差异有显著性（Ｐ＜０．０５，ＲＲ＝２．３０ＲＲ＝４．０２）。对输血量，输血次数及住院天数双向筛选法多元线性逐步回归分析表明，输血量是影响受血者感染ＨＣＶ的主要因素。

EPIDEMIOLOGIC STUDY OF POSTTRANSFUSION HEPATITIS C

Post-transfusion hepatitis C in Jinan area was investigated with historical cohort study. The results showed that in 119 transfusion recipients, ten of them were newly infected with HBV, the infection rate was 8.4%.There was no clinical manifestation in them.31 cases were anti-HCV positive in serum, the positive rate was 26.1%, 14 patients with hepatitis C were found, the attack rate of hepatitis C was 11.7%.Screening of anti-HCV in blood of donors was a main factor for HCV infection of transfusion recipients. The HCV infection rate was 33.8% and attack rate of hepatitis C was 16.9% in the transfusion recipients transfused with the blood without screening of anti-HCV; but the HCV infection rate was 14.6% and attack rate of hepatitis C was 4.2% in the transfusion recipients transfused with the blood which anti-HCV was screened (P<0.05 RR=2.3 RR=4.02).The other factors affecting HCV infection were quanta and times of transfusion, days of hospitalization.