Role of potassium and chlorine channels in the regulation of thymocyte volume in rats |
| |
| Authors: | R. S. Kurbannazarova B. A. Tashmukhamedov R. Z. Sabirov |
| |
| Affiliation: | (1) Laboratory of Molecular Physiology, Institute of Physiology and Biophysics, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan;(2) Department of Biophysics, Uzbekistan National University, Tashkent, Uzbekistan |
| |
| Abstract: | Regulatory decrease in thymocyte volume under conditions of osmotic stress was abolished by potassium and chlorine channel blockers. Osmotic stress-activated chlorine channels belong to 2 pharmacological types. The maxi-anion channel is sensitive to Gd3+. The volume-sensitive outwardly rectifying chlorine channel is inhibited with glybenclamide and phloretin. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 5, pp. 544–547, May, 2008 |
| |
| Keywords: | lymphocytes osmotic stress ion channels |
| 本文献已被 SpringerLink 等数据库收录！ |
|
