高频微波子宫内膜去除术治疗肝硬化异常子宫出血的安全性和有效性

目的探讨高频微波子宫内膜去除术治疗肝硬化患者异常子宫出血的安全性、有效性。方法选择2012年4月至2014年5月收治的26例肝硬化合并异常子宫出血患者,均实施高频微波子宫内膜去除术。结果 26例患者均成功完成手术,平均治疗时间(61.0±18.9)s;术中出血均15 mL;无并发症发生;术后肝硬化相关指标与术前相比,差异无统计学意义(P0.05);贫血、疲劳、烦躁与术前相比明显好转,生活质量明显提高,差异有统计学意义(P0.01)。术后1、3、6、12个月随访,治疗有效率为100%(26/26)、100%(21/21)、100%(19/19)和100(14/14);闭经率分别为88.5%(23/26)、95.2%(20/21)、100%(19/19)和92.9%(13/14);满意率分别为100%、100%、100%和92.31%。结论高频微波子宫内膜去除术用于治疗肝硬化患者异常子宫出血可以获得良好效果,安全性高。

Safety and efficacy of radiofrequency endometrial ablation operation for abnormal uterine bleeding in liver cirrhosis patients

Objective To investigate safety and efficacy of radiofrequency endometrial ablation operation for abnormal uterine bleeding in liver cirrhosis .Methods Twenty six patients with cirrhosis and abnormal uterine bleeding in our hospital from April 2012 to May 2015 were enrolled ,and received radiofrequency endometrial ablation operation .Results The procedures was completed successfully in all the patients .The mean operation time was (61 .0 ± 18 .9)s (ranged from 37 to 108 s) .During the operation ,the blood loss was less than 15m1 ,no complications occurred .No significant difference of variables related to liver disease between variables obtained at 1 month post‐NovaSure treatment with those obtained at baseline in the cirrhotic(P> 0 .05) .There are significant improvement of anemia ,fatigue ,dysphoria and QoL scores was observed at after the therapy compared to those at baseline (P< 0 .001) .The rate of amenorrhoea was 88 .5% (23/26)、95 .2% (20/21)、100% (19/19) and 92 .9% (13/14) ,and the rate of efficacy satisfaction was 100% (26/26)、100% (21/21)、100% (19/19) and 100(14/14) ,and the satisfaction rates was 100% 、100% 、100% and 92 .31% at months 1 ,3 ,6 ,and 12 , respectively .Conclusion Radiofrequency endometrial ablation operation shows good efficacy and safety in the treatment of abnormal uterine bleeding in patients with liver cirrhosis .