Enhancement of recovery from mental illness with l‐methylfolate supplementation |
| |
Authors: | Gerald Martone MS MSN PMHNP‐BC |
| |
Institution: | Alaska Psychiatric Institute, Anchorage, Alaska, USA |
| |
Abstract: | People suffering from depression, schizophrenia, and dementia often have measurably lower levels of serum folate compared to people not experiencing psychiatric disorders. Augmentation of SSRI and SNRI antidepressant medications with l ‐methylfolate has been demonstrated to increase their effectiveness and onset of action. Even the use of l ‐methylfolate as a stand‐alone monotherapy has been observed to exert antidepressant properties. The role of folate in mental illness has been known for many decades, but the strategic use of l ‐methylfolate supplementation has not yet been accepted as a standard regimen. It is the proposal of this paper that advanced nurse practitioners should consider the use of l ‐methylfolate as an adjunct to antidepressant medications at the initiation of therapy as part of a standard regimen in their clinical practice. |
| |
Keywords: | augmentation folate folic acid l‐methylfolate methylfolate supplements |
|
|