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Localization of nerve-specific protein antigens on the surface membrane of neurons and glial cells of Helix pomatia
Authors:N V Piven'  V I Khichenko  M B Shtark
Abstract:The existence of cross protein antigens common to several species of invertebrates and vertebrates on the membrane of neurons and glial cells of Helix pomatia was demonstrated in vitro by Coons' immunofluorescence method. The presence of nerve-specific protein S-100 on the membrane of these cells was established. The antigenic heterogeneity of membranes of a population of neurons also was observed. Differences were found in the concentrations of antigens on the somatic and axon membranes. The character of distribution of specific fluorescence indicates possible qualitative and (or) quantitative differences in the content of nervespecific proteins in different areas of the neuron membrane.Laboratory of Central Mechanisms of Regulation and Control, Institute of Clinical and Experimental Medicine, Siberian Branch, Academy of Medical Sciences of the USSR, Novosibirsk. (Presented by Academician of the Academy of Medical Sciences of the USSR V. P. Kaznacheev.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 88, No. 9, pp. 299–301, September, 1979.
Keywords:brain-specific antigen  neurons of invertebrates  immunofluorescence
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