滑膜细胞代谢在类风湿关节炎中作用的研究进展

类风湿关节炎（RA）是一种全身性、难治性、自身免疫性疾病，其主要病理特点是滑膜细胞增生、衬里层增厚、多种炎性细胞浸润、血管翳形成等。这些病理改变是多种因素共同作用的结果。近年来，针对RA的发生机制展开了大量的实验研究，研究方向集中在滑膜增生、炎性因子、基因调控等方面。本文聚焦于滑膜细胞代谢在RA中的作用研究进展进行综述，期望能为其临床诊治提供新的模式及靶点。

Research progress of synovial cell metabolism in rheumatoid arthritis

Rheumatoid arthritis (RA) is a kind of systematic refractory autoimmune disease and is pathologically featured by proliferation of synovial cells, thickening of the lining layer, infiltration of multiple inflammatory cells, formation of pannus, etc. These pathological changes are a result of multiple factors. In recent years, many studies on the occurrence mechanism of RA have been performed, which mainly focused on the synovial hyperplasia, inflammatory factor, gene regulation, etc. This article focuses on the research progress of synovial cell metabolism in RA, with the aim of providing new model and new target for the treatment of RA.