| 电刺激在视网膜退行性疾病治疗中的研究进展 |
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| 引用本文： | 于莎莎,汤欣,赵云,李永康,赵健.电刺激在视网膜退行性疾病治疗中的研究进展[J].国际眼科杂志,2019,19(5):783-786. |
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| 作者姓名： | 于莎莎 汤欣 赵云 李永康 赵健 |
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| 作者单位： | 中国天津市眼科医院 天津市眼科学与视觉科学重点实验室 天津市眼科研究所 天津医科大学眼科临床学院,中国天津市眼科医院 天津市眼科学与视觉科学重点实验室 天津市眼科研究所 天津医科大学眼科临床学院,中国天津市眼科医院 天津市眼科学与视觉科学重点实验室 天津市眼科研究所 天津医科大学眼科临床学院,中国香港,香港大学眼科学系,中国香港,香港大学眼科学系 |
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| 摘 要： | 视网膜病变和视神经损伤导致视觉信息无法正常传递到视觉中枢,对患者的视觉功能以及生活质量产生严重影响。临床工作中常见的眼部疾病如青光眼、外伤性视神经病变、视网膜色素变性等均伴有视网膜神经元和/或视神经的退行性病变,而目前临床上常用的神经保护疗法疗效非常有限。近年研究表明,电刺激对视网膜和视神经具有神经保护和促进再生的作用。本文通过对电刺激在眼科应用的进展进行综述,总结电刺激治疗的相关机制,推动电刺激在眼科疾病研究和应用中的发展。
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| 关 键 词： | 视网膜 视神经 电刺激 神经保护 神经再生 |
| 收稿时间： | 2018/10/1 0:00:00 |
| 修稿时间： | 2019/3/28 0:00:00 |
Development of electrical stimulation treatment in retina degeneration diseases |
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| Sha-Sha Yu,Xin Tang,Yun Zhao,Wing-Hong Lee and Kin Chiu.Development of electrical stimulation treatment in retina degeneration diseases[J].International Journal of Ophthalmology,2019,19(5):783-786. |
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| Authors: | Sha-Sha Yu Xin Tang Yun Zhao Wing-Hong Lee and Kin Chiu |
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| Institution: | Tianjin Eye Hospital,Tianjin Key Laboratory of Ophthalmology and Vision Science; Tianjin Eye Institute; Clinical College of Ophthalmology of Tianjin Medical University, Tianjin 300020, China,Tianjin Eye Hospital,Tianjin Key Laboratory of Ophthalmology and Vision Science; Tianjin Eye Institute; Clinical College of Ophthalmology of Tianjin Medical University, Tianjin 300020, China;,Tianjin Eye Hospital,Tianjin Key Laboratory of Ophthalmology and Vision Science; Tianjin Eye Institute; Clinical College of Ophthalmology of Tianjin Medical University, Tianjin 300020, China,Department of Ophthalmology, the University of Hong Kong, Hong Kong 999077, China and Department of Ophthalmology, the University of Hong Kong, Hong Kong 999077, China |
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| Abstract: | Retinal diseases and optic nerve injury blocked visual signal transduction from retinal neurons to visual cortex, which would cause significant influence on patients'' visual function and life quality. In clinic, glaucoma, traumatic optic neuropathy, and retinitis pigmentosa and so on are accompanied with degeneration of retinal neurons or optic nerve. However, efficient neuro-protective treatment is limited. Currently, studies suggested neuro-protective and regenerative effect of electrical stimulation treatment on retinal neurons and optic nerves. In this study, we reviewed the application of electrical stimulation in ophthalmology and summarized the possible mechanism, aiming to promote the development of electrical stimulation in the study and treatment of eye diseases. |
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| Keywords: | retina optic nerve electrical stimulation neuro-protection neuro-regeneration |
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