急诊胆囊炎不同手术方式对机体的应激及免疫功能的影响

目的研究急诊腹腔镜胆囊切除术对机体的应激、免疫功能的影响.方法 70例急性胆囊炎患者分为两组：急诊腹腔镜胆囊切除术（LC）组35例, 急诊开腹胆囊切除术组（OC）35例.所有患者术前静脉血检测应激指标C-反应蛋白（CRP）、白介素-6（IL-6）、白细胞计数（WBC）和免疫功能指标（IgG、 IgM、补体C3）,术后第 2 天清晨输液前复查上述指标.结果急诊LC组术后WBC、CRP、IL-6及IgG、IgM、补体C3测定值与术前比较,差异均无统计学意义（P＞0.05）;急诊OC术后WBC、CRP、IL-6及IgG 、IgM、补体C3等测定值与急诊LC术后比较,差异均有统计学意义（P＜0.05）.结论急诊腹腔镜胆囊切除术对机体应激反应的影响小于急诊开腹胆囊切除术.

Influences of Two Modus Operandi in Acute Cholecystitis on Stress and Immune Function

Objective To study the influences of two operation methods in acute cholecystitis on stress and immune function.Methods Seventy patients with acute cholecystitis were divided into two groups.Thirty and five underwent laparoscopic cholecystectormy(LC) and 35 underwent open cholecystectormy(OC).CRP,IL-6, white blood count,IgG,IgM and C3 levels were tested preoperatively and postoperatively day 1 in the morning.Results No difference occurred in LC group preoperatively and postoperatively in CRP,IL-6,white blood count,IgG,IgM and C3 levels(P>0.05).Postoperative white blood count,CRP,IL-6,IgG,IgM and C3 levels had difference(P<0.05) between OC and LC group.Conclusion Emergency LC has less influence on stress reaction than emergency OC.