| 快速凝结复合羟基磷灰石陶瓷粉生物相容性评价 I.毒性与细胞相容性研究 |
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| 引用本文： | 刘月辉,文三立,肖尊文.快速凝结复合羟基磷灰石陶瓷粉生物相容性评价 I.毒性与细胞相容性研究[J].江西医学院学报,1998(2). |
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| 作者姓名： | 刘月辉 文三立 肖尊文 |
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| 作者单位： | Department of Oforhinolaryngology，First Affiliated Hospital，Jiangxi Medical College，Nanchang 330006 |
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| 基金项目： | 国家“八五”重点攻关基金 |
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| 摘 要： | 对自行研制的快速凝结复合羟基磷灰石陶瓷粉的毒性及细胞相容性进行研究。实验包括：（１）亚急性毒性实验；（２）溶血试验；（３）皮内试验；（４）热原试验；（５）体外细胞毒性试验。结果表明该材料安全无毒、无溶血性、对皮肤无剌激，不含热原物质，具有良好的细胞相容性，可广泛应用于临床。
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| 关 键 词： | 陶瓷／毒性 羟基磷灰石类／毒性 细胞相容性 |
Biocompatibility Evaluation of Fast Self setting Complex Hydroxylapatite Ceramic Powder I.Study on Toxicity and Cytocompatibility |
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| Liu Yuehui,Wen Shanli,Xiao Zunwen.Biocompatibility Evaluation of Fast Self setting Complex Hydroxylapatite Ceramic Powder I.Study on Toxicity and Cytocompatibility[J].Acta Academiae Medicinae Jiangxi,1998(2). |
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| Authors: | Liu Yuehui Wen Shanli Xiao Zunwen |
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| Institution: | Liu Yuehui Wen Shanli Xiao Zunwen * |
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| Abstract: | In order to study the toxicity and cytocompatibility of fast self setting complex hydroxylapatite ceramic powder having been developed recently,the authors did the experiments:(1)subacute systemic toxicity by oral route;(2)themolytic test;(3)intradermal injection test;(4)thermogenic test and (5)cytotoxic test in vitro.The results showed that the fast self setting complex hydroxylapatite ceramic powder had no toxicity,no themolytic activity,no cytotxicity,no irritation to skin and does not contain thermogenic material.It was a kind of good biocompatible materials and could be used in clinic widely. |
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| Keywords: | ceramics/toxicity hydroxylapatite/toxicity cytocompatibility ** |
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