MSCT评价冠状动脉软斑块狭窄程度与左心室收缩功能

目的 探讨MSCT在评价冠状动脉软斑块狭窄的同时测定左心室功能的临床应用价值。方法 回顾性分析232例接受MSCT冠状动脉造影的患者,包括46例单纯软斑块致冠状动脉狭窄(软斑块组,又分为轻、中、重度狭窄组)和186例冠状动脉正常者(正常组)。以测量血管直径法,按照冠状动脉狭窄程度分为I~Ⅳ组,并计算左心室舒张末期容积(EDV)、左心室收缩末期容积(ESV)、左心室每搏输出量(SV)、左心室射血分数(EF)。结果 轻度、中度狭窄组与正常组间EF的差异无统计学意义,其他组间差异有统计学意义(P＜0.01);轻度狭窄组、中度狭窄组与正常组间ESV值差异性无统计学意义,其他组间差异有统计学意义(P＜0.01);EDV、SV、心率组间差异无统计学意义(P＞0.05)。结论 冠状动脉CTA可评估冠状动脉狭窄情况。当冠状动脉管径狭窄＞50%时,左心室收缩功能有不同程度下降;当冠状动脉管径狭窄＞75%时,左心室收缩功能下降明显。MSCT可准确、可靠地定量评价冠状动脉硬化狭窄及左心室收缩功能。

MSCT assessment of coronary artery soft plaque stenosis and left ventricular systolic function

Objective To observe the clinical application value of coronary artery soft plaque stenosis,and left ventricular function with MSCT in patients with suspected coronary artery disease.Methods Totally 232 patients were retrospectively analyzed with MSCT coronary angiography,including 46 of pure soft plaque and 186 of coronary artery without stenosis.All patients were divided into 4 groups according to coronary vessel diameter(normal,mild stenosis,moderate stenosis,severe stenosis),and left ventricular end-dia...