通络舒液治疗早期类风湿关节炎的临床观察

目的 探讨采用纯中药制剂通络舒液治疗早期类风湿关节炎的临床疗效.方法 将100例类风湿关节炎患者采用单盲法随机分为两组各50例,治疗组服用通络舒液,150 ml/次,2次/d.对照组服用双氯芬酸钠缓释片(迪根),1片/次,2次/d;甲氨碟呤7.5 mg/次,1次/周.结果 治疗组可明显改善早期类风湿关节炎的症状、体征、生化指标及Ⅰ期、Ⅱ期关节周围软组织肿胀,抑制骨质疏松,并阻断向Ⅲ期的软骨破坏的进展.结论 通络舒液治疗类风湿关节炎有效.

Clinical Observation on the Treatment of Rheumatoid Arthritisin Early Stage with TongLuoShu Liquid

Objective To investigate the clinical efficacy of TongluoShu Liquid in treating rheumatoid arthritis at early stage. Methods 100 cases were randomly recruited into a control group and a treatment group with 50 cases in each group. The treatment group was given TongluoShu liquid, 150ml / time, twice a day; and the control group was given Diclofenac Sodium Sustained Release Tablets (Deegan), one granule for each time, twice a day, and Methotrexate 7.5mg / time, once per week. Results In the treatment group, symptoms, signs and biochemical indicators were significantly improved, and the swelling of the soft tissue around the joints in stage Ⅰ and Ⅱ were also reduced. Besides, osteoporosis was controlled and the progress of destruction to the cartilage of stage Ⅲ was detained, though there was no statistical difference between the two groups after the treatment. Conclusion ShuTongluo liquid is a safe and effective medicine with less adverse reactions in treating rheumatoid arthritis.