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| 马桑内酯对大鼠海马脑片细胞外Na+、K+活度的影响 | |
| 引用本文： | 邹飞,倪再玉,袁太宁,王尊琼,郑世玲,王阿敬. 马桑内酯对大鼠海马脑片细胞外Na+、K+活度的影响[J]. 湖北民族学院学报(医学版 ), 2001, 18(2): 8-10 |
| 作者姓名： | 邹飞 倪再玉 袁太宁 王尊琼 郑世玲 王阿敬 |
| 作者单位： | 1. 三峡大学医学院生理教研室, 2. 三峡大学医学院药理教研室, 3. 华中科技大学同济医学院实验医学研究中心, |
| 基金项目： | 国家自然科学基金资助项目(39330210) |
| 摘 要： | 目的探讨癫痫过程中神经细胞Na |
| 关 键 词： | 马桑内酯 海马脑片 Na^＋ K^＋ CL 癫痫 |
| 文章编号： | 1008-8164(2001)02-0008-03 |
The Effect of Coriaria Lactone on Extracellular Sodium and Potassium Ionic Activities of Hippocampal Slice in Rat |
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| ZOU Fei,NI Zai-yu,YUAN Tai-ning,et al. The Effect of Coriaria Lactone on Extracellular Sodium and Potassium Ionic Activities of Hippocampal Slice in Rat[J]. Journal of Hubei Institute For Nationalities(Medical Edition), 2001, 18(2): 8-10 | |
| Authors: | ZOU Fei NI Zai-yu YUAN Tai-ning et al |
| Abstract: | Objective To study the changes of ionic activity of extracellular sodium and potassium (o?o) of hippocampal slice perfused by coriaria lactone (CL).Methods The sodium ion (Na +) and potassium ion (K +) selective microeletrodes were used to measure alteration of the o and the o of perfused hippocampal slice with CL. Results 30s after perfusing of CL into hippocampal slice, the o decreased 10 mmol/L compared with control values ( P <0.01) and did not return to the control level during the experiment (20min) .1min ?2min ?3min ?5min and 10min after perfusing of CL into hippocampal slice,The o increased 3.3mmol/L ?4.8mmol/L ?4.9mmol/L? 6.5mmol/L and 8.8 mmol/L respectively compared with control values ( P <0.01), 10 min after, the o always kept the level. Conclusion: The influx of Na + and the flux of K + occurred during perfusing hippocampal slice with CL . |
| Keywords: | coriaria lactone hippocampal slice sodium potassium |
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