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核电站周边居民染色体畸变和淋巴细胞亚群分析
引用本文:鹿伟,宣志强,陈玉满,夏勇,陈苘,宋燕华,徐彩菊. 核电站周边居民染色体畸变和淋巴细胞亚群分析[J]. 中华放射医学与防护杂志, 2013, 33(6): 645-647
作者姓名:鹿伟  宣志强  陈玉满  夏勇  陈苘  宋燕华  徐彩菊
作者单位:310051 杭州, 浙江省疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心
基金项目:浙江省医药卫生科技计划项目(2010KYB028)
摘    要:目的 探讨核电站长期运行对周边居民健康的影响,了解核电站长期运行下周边居民健康基础资料。方法 按照离核电站远近,选取0~10 km、10~20 km、20~30 km 3个调查区和对照区,采集血样,分析外周血淋巴细胞染色体畸变和淋巴细胞亚群。结果 0~10 km、10~20 km、20~30 km调查区和对照区畸变细胞率分别为0.157%、0.167%、0.070%、0.111%,差异无统计学意义。淋巴细胞亚群分析0~30 km范围3个调查区T淋巴细胞、辅助T淋巴细胞、抑制T淋巴细胞、B淋巴细胞、NK细胞均正常,各区之间差异无统计学意义。结论 该核电站在正常运行条件下,尚未对周边居民的健康产生明显影响。

关 键 词:核电站  染色体畸变  淋巴细胞亚群
收稿时间:2013-04-25

Detection of chromosome aberration and lymphocytes subsets of the population around a nuclear power plant
LU Wei,XUAN Zhi-qiang,CHEN Yu-man,XIA Yong,CHEN Qing,SONG Yan-hua and XU Cai-ju. Detection of chromosome aberration and lymphocytes subsets of the population around a nuclear power plant[J]. Chinese Journal of Radiological Medicine and Protection, 2013, 33(6): 645-647
Authors:LU Wei  XUAN Zhi-qiang  CHEN Yu-man  XIA Yong  CHEN Qing  SONG Yan-hua  XU Cai-ju
Affiliation:Department of Physicochemistry and Toxicology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Department of Physicochemistry and Toxicology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Department of Physicochemistry and Toxicology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Department of Physicochemistry and Toxicology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Department of Physicochemistry and Toxicology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Department of Physicochemistry and Toxicology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Department of Physicochemistry and Toxicology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
Abstract:Objective To study the effect of the long-term operation of a nuclear power plant (NPP) on population health, and to collect the health related data of the population around (NPP). Methods Four research areas, named 0-10 km area, 10-20 km area, 20-30 km area and control area, were set up interms of the distance from the nuclear power plant. Human blood samples were collected to detect chromosome aberration and lymphocytes subsets. Results The rates of cells with chromosome aberration at 0-10 km area, 10-20 km area, 20-30 km area and control area were 0.157%, 0.167%, 0.070% and 0.111%, respectively. The differences of rates in the four areas were not statistically significant. The percentages of T lymphocytes, helper T lymphocytes, suppressor T lymphocytes, B lymphocytes and natural killer lymphocytes were all normal. The difference of percentages among 0-10 km area, 10-20 km area, 20-30 km area were not statistically significant. Conclusions In the operational condition, less significant impact is caused to the population around nuclear power plant.
Keywords:Nuclear power plant  Chromosome aberration  Lymphocytes subsets
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