医用羧甲基壳多糖用于改善甲状腺术后颈部活动舒适度的效果分析

目的研究医用羧甲基壳多糖改善甲状腺术后颈部活动舒适度的效果。 方法选择郑州人民医院2013年1月至9月收治的96例甲状腺疾病手术患者的临床资料，分为试验组和对照组，试验组术中使用医用羧甲基壳多糖涂抹在气管与颈部肌群间或颈前肌群与皮瓣间，对照组不使用医用羧甲基壳多糖，评估甲状腺术后30 d及90 d颈部活动舒适度。 结果甲状腺术后30 d及90 d试验组患者颈部活动舒适度明显高于对照组，差异有统计学意义（Z₁=-5.652，P₁=0.000；Z₂=-6.418，P₂=0.000）。 结论医用羧甲基壳多糖具有改善甲状腺患者术后颈部活动舒适度的效果，值得临床推广应用。

Effects of medical carboxymethyl-chitosan on improving patients' neck activity and comfort after thyroidectomy

ObjectiveTo study the effects of medical carboxymethyl-chitosan on improving pa-tients' neck activity and comfort after thyroid surgery. MethodsClinical data of 96 patients, who re-ceived thyroid surgery in People's Hospital of Zhengzhou from January to September 2013 were analyzed. They were divided into 2 groups: experimental group and control group. In experimental group, medical carboxymethyl-chitosan was placed between the trachea and the anterior muscles of the neck, between the anterior muscles of the neck and the skin flap after patients' thyroid surgery. But medical carboxymethyl-chitosan was not used in the control group. The patients' neck activity and comfort were evaluated 30 and 90 days after thyroid surgery. ResultsThe patients' neck activity and comfort under the incision were significantly improved in the experimental group than the control group at day 30 and day 90 after thyroid surgery (Z₁=-5.652, P₁=0.000; Z₂=-6.418, P₂=0.000). ConclusionsMedical carboxymethyl-chitosan has a good effect on improving patients' neck activity and comfort after thyroid surgery. It is worth to be applied and extended in the clinic.