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虚拟导航超声造影与常规超声造影定位检测肝局灶性病变的比较
引用本文:李凯,袁树芳,郑荣琴,贺需旗,苏中振,谢海琴. 虚拟导航超声造影与常规超声造影定位检测肝局灶性病变的比较[J]. 中华超声影像学杂志, 2011, 20(5). DOI: 10.3760/cma.j.issn.1004-4477.2011.05.006
作者姓名:李凯  袁树芳  郑荣琴  贺需旗  苏中振  谢海琴
作者单位:中山大学附属第三医院超声科,中山大学超声诊断与介入超声研究所,广州,510630
基金项目:广东省科技计划项目,2007年公益性行业科研专项经费
摘    要:目的 比较虚拟导航超声造影与常规超声造影检出二维超声显示困难肝局灶性病变的差异,探讨虚拟导航超声造影的应用价值.方法 47个CT或MR提示但二维超声无法显示的肝局灶性病变,分别行虚拟导航超声造影和常规超声造影,对比两种造影方法的病灶检出率.结果 常规超声造影和虚拟导航超声造影的病灶检出率分别为 36.2%(17/47)和 78.7%(37/47),后者明显高于前者(P<0.01).虚拟导航超声造影时图像融合成功率达100%,平均对位用时5 min.当病灶位于肝边缘受肋骨或肺气影响、肝实质背景杂乱及病灶异常灌注时相较短或灌注差异不明显时,虚拟导航超声造影比常规超声造影更容易定位并检出病灶.结论 虚拟导航超声造影可明显提高二维超声无法显示肝局灶性病变的造影检出率.
Abstract:
Objective To evaluate virtual navigation assisted contrast-enhanced ultrasound(VN-CEUS) by comparing VN-CEUS with routine CEUS in detecting focal liver lesion(FLL) invisible in B-mode ultrasound(BUS).Methods Forty-seven FLLs invisible in BUS were identified by CT/MR,and received VN-CEUS and routine CEUS respectively.Results The detection rate of VN-CEUS and routine CEUS were 78.7%(37/47) and 36.2%(17/47),the former was much higher than the later (P<0.01).In all the cases,fusion of CT/MR with ultrasound was achieved successfully and average time for image fusion was 5 min.compared with routine CEUS,VN-CEUS could more easily find FLLs shadowed by lung or ribs,FLLs in inhomogeneous liver background,and FLLs with brief or inapparent abnormal enhancement.ConclusionsVN-CEUS can greatly improve the detection rate of FLL that was invisible in BUS.

关 键 词:超声检查  微气泡  肝疾病  虚拟导航系统

Virtual navigation assisted contrast-enhanced ultrasound for focal liver lesion invisible in B-mode ultrasound
LI Kai,YUAN Shu-fang,ZHENG Rong-qin,HE Xu-qi,SU Zhong-zhen,XIE Hai-qin. Virtual navigation assisted contrast-enhanced ultrasound for focal liver lesion invisible in B-mode ultrasound[J]. Chinese Journal of Ultrasonography, 2011, 20(5). DOI: 10.3760/cma.j.issn.1004-4477.2011.05.006
Authors:LI Kai  YUAN Shu-fang  ZHENG Rong-qin  HE Xu-qi  SU Zhong-zhen  XIE Hai-qin
Abstract:Objective To evaluate virtual navigation assisted contrast-enhanced ultrasound(VN-CEUS) by comparing VN-CEUS with routine CEUS in detecting focal liver lesion(FLL) invisible in B-mode ultrasound(BUS).Methods Forty-seven FLLs invisible in BUS were identified by CT/MR,and received VN-CEUS and routine CEUS respectively.Results The detection rate of VN-CEUS and routine CEUS were 78.7%(37/47) and 36.2%(17/47),the former was much higher than the later (P<0.01).In all the cases,fusion of CT/MR with ultrasound was achieved successfully and average time for image fusion was 5 min.compared with routine CEUS,VN-CEUS could more easily find FLLs shadowed by lung or ribs,FLLs in inhomogeneous liver background,and FLLs with brief or inapparent abnormal enhancement.ConclusionsVN-CEUS can greatly improve the detection rate of FLL that was invisible in BUS.
Keywords:Ultrasonography  Microbubbles  Liver diseases  Virtual navigation system
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